Integrated mechanistic and data-driven modelling for multivariate analysis of signalling pathways

Fei Hua, Sampsa Hautaniemi, Rayka Yokoo, Douglas A Lauffenburger
Table 1

COST matrix for transition from insensitive-response cluster (I) to sensitive-response cluster (III).

I1I2I3I4I5I6I7I8I9
III12.182.671.921.6711.771.921.941.95
III22.011.522.52.51.522.512.492.51.52
III32.982.49212.51.871.921.882.99
III43.313.792.653.612.181.961.653.61
III53.073.553.072.611.952.612.62.481.46
III62.983.221.992.2212.771.991.961.59
III73.393.232.162.672.7622.173.173
III83.643.153.012.033.32.472.651.544.51